Self-Assembled Polymeric Nanoparticle for Mitochondria-Targeting Drug Delivery

targeting mitochondria HC kANGDr Han Chang Kang, from the Department of Pharmacy, The Catholic University of Korea, Republic of Korea will present his recent research about the Self-Assembled Polymeric Nanoparticle for Mitochondria-Targeting Drug Delivery.

Recently, subcellular targeting drug delivery systems that specifically reach subcellular compartments (e.g., cytosol, nucleus, and mitochondria) of interest have garnered more attention because their action sites for generating therapeutic effects occur not just at the cellular level but at the subcellular level as well. Among them, this presentation will be focused on mitochondria-targeting self-assembled polymer-based nanoparticles for intracellular drug delivery because mitochondria are very significant intracellular organelles for controlling the homeostasis of vital physiological functions and synthesizing bioenergy molecules and their dysfunction leads to a variety of human disorders including neurodegenerative, neuromuscular, cardiac, and metabolic diseases. The significance of the mitochondria in disease allows a broad spectrum of therapeutics to strengthen or weaken their intrinsic or newly-introducing functions. Thus, the presentation will introduce the mitochondria-targeting drug delivery systems designed by me and my collaborators. 

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