Exercise-induced, mitochondrial-mediated cell death in Arrhythmogenic Cardiomyopathy

Targeting Mitochondria 2021 Stephen-P. ChelkoDr. Stephen Chelko from Department of Biomedical Sciences, Florida State University, USA will join the Targeting Mitochondria 2021 Congress which will be held on October 27-29, 2021 and will give a presentation on his recent  work in Science Translational Medicine on the Exercise-induced, mitochondrial-mediated cell death in Arrhythmogenic Cardiomyopathy.

Summary of talk: Arrhythmogenic Cardiomyopathy (ACM) is a familial heart disease with a high incidence of sudden cardiac death in the young and in athletes. Reduced penetrance and variable expressivity complicate early diagnosis and management of ACM. More and more evidence on the deleterious impact of exercise in ACM is growing, yet these studies all implicate the arrhythmic risk and/or hemodynamic load on the heart in response to exercise. New evidence demonstrates that endurance exercise leads to mitochondrial dysfunction, ROS generation, and large-scale myocyte death in ACM.

 

Targeting Mitochondria 2021 Congress
October 27-29, 2021
Berlin, Germany & Virtual Congress
www.targeting-mitochondria.com