Targeting Mitochondria 2020 - Preliminary Agenda

 Wednesday, October 28, 2020

Mitochondria Workshop 2020
How to Evaluate Mitochondria Function?

- Online Workshop -

 Full agenda and information, please follow this link

Thursday, October 29, 2020
Targeting Mitochondria 2020 Agenda

- Day 1 -

Welcome Note & Introduction Remarks
Volkmar Weissig, President of the World Mitochondria Society, Midwestern University, USA
Marvin Edeas, University Paris Descartes, Inserm 1016, Institute Cochin, France


Session 1 - Recent Advances on Mitochondrial Dysfunctions and Dynamics in Chronic Diseases: The Mechanisms

  • Mitochondria & Viral Infection
  • Mitochondria & Metabolic Syndrome
  • Mitochondria & Neurodegenerative Diseases Mitochondria & Cancer

Roles for mitochondrial dysfunction in Alzheimer’s disease
Benedict Albensi, Max Rady College of Medicine - University of Manitoba, Canada

FBXL4 Deficiency leads to increased clearance of Mitochondria
Nils-Göran Larsson, Karolinska Institutet, Sweden

Down Syndrome: Role of hydrogen sulfide overproduction in the pathogenesis of mitochondrial dysfunction
Csaba Szabo, Université de Fribourg, Switzerland

Mitochondrial dysfunction in autism is distinct from mitochondrial disease
Richard E. Frye, Phoenix Children's Hospital, USA


Session 2 - Extracellular Mitochondria: The Intriguing Localization and Role

The Cell-free respiratory competent mitochondria in blood: Strategic role and application
Alain Thierry, Montpellier Cancer Research Institute, INSERM, France


Session 3 - Targeting Intra & Extra Mitochondria in COVID-19 Pathogenesis: An Emerging Strategy

  • The Pathophysiological Role of Intra & Extra Mitochondria in COVID-19
  • Role of Iron, Ferroptosis and Oxidative Stress

Mitochondria and microbiota dysfunction in COVID-19 pathogenesis
Marvin Edeas
University Paris Descartes, Inserm 1016, Institute Cochin, France


Session 4 - An update: The Challenge of Qualitative and Quantitative Assessment of Mitochondrial Function in vitro and in vivo

  • Extra Mitochondria Evaluations
  • Mitochondria Quality Control
  • Mitochondria Devices: New methods to detect Mitochondria Dysfunction
  • Mitochondria as Biomarkers Presentation of Practical Cases

Mitochondria devices: New methods to detect mitochondria dysfunction
Naïg Gueguen,  MitoVasc Institute, Angers University Hospital Center, France

The Challenge of Qualitative and Quantitative Assessment of Mitochondrial Function in Vitro And in Vivo: What We Know in 2020?
Egbert Mik, University Medical Center Rotterdam, The Netherlands

Control of cellular bioenergetics by cytosolic calcium
Franck Norbert Gellerich, Otto-von-Guericke University, Germany


Short Oral Presentations of Day 1:

Impact of Tafazzin knockout on mitochondrial and cellular properties
Gayatri Jagirdar, University medicine Greifswald, Germany

Retrograde signaling by an MT-DNA-Encoded non-coding RNA preserves mitochondrial bioenergetics
Anna Blumental-Perry, State University of New York, USA

Aralar sequesters GABA into hyperactive mitochondria causing social behavior deficits
Alexandros Kanellopoulos, University of Lausanne, Switzerland

Alcohol induces mitochondrial dysfunction in human induced pluripotent Stem cell-derived three-dimensional Cerebral Organoids
Xiaowen Bai, Medical College of Wisconsin, USA

Overexpression of MitoNEET in osteoblasts leads to impaired bone mass and energy metabolism
Anyonya Guntur, Maine Medical Center Research Institute, USA

Diet-dependent gut microbiota modulates adult neurogenesis through mitochondrial stress modulation
Susana Solá, Universidade de Lisboa, Portugal

Mitochondrial dysfunction in skeletal muscle of a mouse model (OIM) of severe human osteogenesis imperfecta
Victoria Gremminger, University of Missouri, USSA

Aralar sequesters GABA into hyperactive mitochondria causing social behavior deficits
Alexandros Kanellopoulos, University of Lausanne, Switzerland

End of the first day


Friday, October 30, 2020
Targeting Mitochondria 2020 Agenda
- Day 2 -

Session 5 - Symposium: Non-Coding RNAs in Nuclear-Mitochondrial Crosstalk: Applications for RNA Medicine
Chairpersons: Eric Barrey, GABI & (INRAE) and Nina Entelis (UNISTRA) - France

Introduction: Variety of non-coding RNA imported and encoded in mitochondria
Eric Barrey, University Paris-Saclay, INRAE, AgroParisTech, France

Molecular mechanisms of ncRNAs transport into mitochondria: emerging approaches and potential gene therapy applications
Nina Entelis, UNISTRA, France

Long non-coding RNA SAMMSON and beyond: uncoupling cytosolic and mitochondrial-translation as an effective anti-melanoma strategy
Eleonora Leucci, Laboratory for RNA Cancer Biology, Department of Oncology, KU Leuven, Belgium

Targeting long non-coding mitochondrial RNA for cancer therapy
Veronica Burzio, Universidad Andrés Bello, Fundación Ciencia & Vida, Andes Biotechnologies, Republic of Chile

Round table: Prospective on other mitochondrial gene therapies
moderated by Ivan Tarassov, UNISTRA, Strasbourg, France


Session 6 - Strategies to Target Mitochondria: Clinical Trials and Potential Mitochondria-based Therapies

  • Strategies to Target Stem Cells Strategies to Target miRNA
  • Strategies to Target Extracellular Mitochondria
  • Strategies to Replace Mitochondria Clinical & Therapeutic Directions

Neurodegeneration and Mitochondria
Ming Guo,
UCLA David Geffen School of Medicine, USA

Enhanced axonal response of mitochondria to demyelination offers neuroprotection: implications for multiple sclerosis
Don Mahad, University of Edinburgh, United Kingdom

Session 7: Mitochondria Innovations 2020

Short Oral Presentations of Day 2:

Targeting the mitochondrial protein MitoNEET with NL-1 provides protection in cerebral ischemic re-perfusion-injury
Werner Geldenhuys, West Virginia University, USA

Low 3-Hydroxyisobutyrate (3-HIB) and high methylmalonic Acid (MMA) levels in plasma reflect increased hepatic fatty acid oxidation
Mona Synnøve Nilsen, University of Bergen, Norway

Liposomes and mesoporous silica nanoparticles non-covalently modified with triphenylphosphonium cation
Lucia Zakharova, FRC Kazan Scientific Center of RAS, Russian Federation

Mitochondria: A potential target for adaptation in Ladakhis
Swati Sharma, Panjab University, India

18:00 Conclusion of Targeting Mitochondria 2020
Targeting Mitochondria Awards:
  • Scientific Contribution of the year
  • Short Oral Contribution
  • Poster Contribution
  • Industrials Innovations
18:15 Targeting Mitochondria 2020 Awards
18:30 End of Targeting Mitochondria 2020

If you wish to submit your abstract for a major talk, Short oral presentation or Poster, please follow the link below:

submit your abstract


Print the Agenda here