Mitochondrial potassium channels: new regulation mechanism?


Prof. Adam Szewczyk from Nencki Institute of Experimental Biology, Warsaw, Poland will present study on "Mitochondrial potassium channels: new regulation mechanism?" during the Mitochondria congress which will be held in October 23-25, 2018, at Berlin, Germany.

Prof. Szewczyk will present the most interesting issues regarding function, regulation and pharmacology of the mitochondrial potassium channels. There are eight potassium channels known to contribute to the potassium permeability of the inner mitochondrial membrane: ATP-regulated channel, calcium-regulated channels of large, intermediate and small conductance, voltage-regulated Kv1.3 and Kv7.4 channels, two-pore-domain TASK-3 channel and SLO2 channel. The primary function of the mitochondrial potassium channels is regulation of the mitochondrial membrane potential. Additionally, mitochondrial potassium channels alter cellular respiration, regulation of the mitochondrial volume and ROS synthesis.


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